bmi1 sirna Search Results


bmi 1 sirna  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology bmi 1 sirna
Bmi 1 Sirna, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmi1+sirna/Bmi-1+siRNA/pmc08472307-133-0-5
Average 93 stars, based on 1 article reviews
bmi 1 sirna - by Bioz Stars, 2026-09
93/100 stars
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knockdown bmi1 gene  (Cell Signaling Technology Inc)
93
Cell Signaling Technology Inc knockdown bmi1 gene
A Representative images of <t>BMI1</t> staining (green bodies). Nuclei are counterstained with DAPi (blue staining). BMI1 protein can accumulate in CAP bodies (left panel) or has uniform punctate distribution (PcG bodies, right panel). Scale bar: 5 μm. B Stacked bar plot representing the proportion of CAP and PcG bodies in ALDH br and ALDH neg SUM159 cells sorted according to their cell-cycle phase (G0/G1, S, and G2/M). C , D Representative images (left panels) of BMI1 costaining (green foci) with γH2AX (red foci) for cells harboring CAP bodies ( C ) or PcG bodies ( D ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and γH2AX fluorescent signals. E Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/γH2AX colocalization. F , G Representative images (left panels) of BMI1 costaining (green foci) with RAD51 (red foci) for cells harboring CAP bodies ( F ) or PcG bodies ( G ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and RAD51 fluorescent signals. H Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/RAD51 colocalization. I Representative images of BMI1 staining (green bodies) in ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated (CTRL). Nuclei are counterstained with DAPi (blue staining). J Stacked bar plot representing the proportion of CAP and PcG bodies in replicative ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated. K Bar plots representing the proportion of γH2AX-positive cells for each cell subpopulation (replicative ALDH br and ALDH neg SUM159 cells) following 5-aza treatment or in untreated conditions (CTRL). Statistical test used is Student’s t -test. Data represent mean ± SD.
Knockdown Bmi1 Gene, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmi1+sirna/SignalSilence+Bmi1+siRNA+I/pmc08811067-352-9-15
Average 93 stars, based on 1 article reviews
knockdown bmi1 gene - by Bioz Stars, 2026-09
93/100 stars
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bmi1 small interfering rna (sirna)  (Ribobio co)
90
Ribobio co bmi1 small interfering rna (sirna)
A Representative images of <t>BMI1</t> staining (green bodies). Nuclei are counterstained with DAPi (blue staining). BMI1 protein can accumulate in CAP bodies (left panel) or has uniform punctate distribution (PcG bodies, right panel). Scale bar: 5 μm. B Stacked bar plot representing the proportion of CAP and PcG bodies in ALDH br and ALDH neg SUM159 cells sorted according to their cell-cycle phase (G0/G1, S, and G2/M). C , D Representative images (left panels) of BMI1 costaining (green foci) with γH2AX (red foci) for cells harboring CAP bodies ( C ) or PcG bodies ( D ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and γH2AX fluorescent signals. E Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/γH2AX colocalization. F , G Representative images (left panels) of BMI1 costaining (green foci) with RAD51 (red foci) for cells harboring CAP bodies ( F ) or PcG bodies ( G ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and RAD51 fluorescent signals. H Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/RAD51 colocalization. I Representative images of BMI1 staining (green bodies) in ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated (CTRL). Nuclei are counterstained with DAPi (blue staining). J Stacked bar plot representing the proportion of CAP and PcG bodies in replicative ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated. K Bar plots representing the proportion of γH2AX-positive cells for each cell subpopulation (replicative ALDH br and ALDH neg SUM159 cells) following 5-aza treatment or in untreated conditions (CTRL). Statistical test used is Student’s t -test. Data represent mean ± SD.
Bmi1 Small Interfering Rna (Sirna), supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmi1+sirna/sirnas+against+bmi1/pmc05587922-50-0-12
Average 90 stars, based on 1 article reviews
bmi1 small interfering rna (sirna) - by Bioz Stars, 2026-09
90/100 stars
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hsa nanocarrier-mediated bmi1 sirna stability  (NanoCarrier Co)
90
NanoCarrier Co hsa nanocarrier-mediated bmi1 sirna stability
A Representative images of <t>BMI1</t> staining (green bodies). Nuclei are counterstained with DAPi (blue staining). BMI1 protein can accumulate in CAP bodies (left panel) or has uniform punctate distribution (PcG bodies, right panel). Scale bar: 5 μm. B Stacked bar plot representing the proportion of CAP and PcG bodies in ALDH br and ALDH neg SUM159 cells sorted according to their cell-cycle phase (G0/G1, S, and G2/M). C , D Representative images (left panels) of BMI1 costaining (green foci) with γH2AX (red foci) for cells harboring CAP bodies ( C ) or PcG bodies ( D ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and γH2AX fluorescent signals. E Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/γH2AX colocalization. F , G Representative images (left panels) of BMI1 costaining (green foci) with RAD51 (red foci) for cells harboring CAP bodies ( F ) or PcG bodies ( G ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and RAD51 fluorescent signals. H Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/RAD51 colocalization. I Representative images of BMI1 staining (green bodies) in ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated (CTRL). Nuclei are counterstained with DAPi (blue staining). J Stacked bar plot representing the proportion of CAP and PcG bodies in replicative ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated. K Bar plots representing the proportion of γH2AX-positive cells for each cell subpopulation (replicative ALDH br and ALDH neg SUM159 cells) following 5-aza treatment or in untreated conditions (CTRL). Statistical test used is Student’s t -test. Data represent mean ± SD.
Hsa Nanocarrier Mediated Bmi1 Sirna Stability, supplied by NanoCarrier Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmi1+sirna/hsa+nanocarrier+mediated+bmi1+sirna+stability/pm32453568-112-41-44
Average 90 stars, based on 1 article reviews
hsa nanocarrier-mediated bmi1 sirna stability - by Bioz Stars, 2026-09
90/100 stars
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bmi1 sirna  (Biospring)
90
Biospring bmi1 sirna
A Representative images of <t>BMI1</t> staining (green bodies). Nuclei are counterstained with DAPi (blue staining). BMI1 protein can accumulate in CAP bodies (left panel) or has uniform punctate distribution (PcG bodies, right panel). Scale bar: 5 μm. B Stacked bar plot representing the proportion of CAP and PcG bodies in ALDH br and ALDH neg SUM159 cells sorted according to their cell-cycle phase (G0/G1, S, and G2/M). C , D Representative images (left panels) of BMI1 costaining (green foci) with γH2AX (red foci) for cells harboring CAP bodies ( C ) or PcG bodies ( D ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and γH2AX fluorescent signals. E Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/γH2AX colocalization. F , G Representative images (left panels) of BMI1 costaining (green foci) with RAD51 (red foci) for cells harboring CAP bodies ( F ) or PcG bodies ( G ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and RAD51 fluorescent signals. H Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/RAD51 colocalization. I Representative images of BMI1 staining (green bodies) in ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated (CTRL). Nuclei are counterstained with DAPi (blue staining). J Stacked bar plot representing the proportion of CAP and PcG bodies in replicative ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated. K Bar plots representing the proportion of γH2AX-positive cells for each cell subpopulation (replicative ALDH br and ALDH neg SUM159 cells) following 5-aza treatment or in untreated conditions (CTRL). Statistical test used is Student’s t -test. Data represent mean ± SD.
Bmi1 Sirna, supplied by Biospring, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmi1+sirna/bmi1+sirna/pm17148583-51-2-61
Average 90 stars, based on 1 article reviews
bmi1 sirna - by Bioz Stars, 2026-09
90/100 stars
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bmi1 human sirna oligo duplex  (OriGene)
N/A
BMI1 Human 3 unique 27mer siRNA duplexes 2 nmol each
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bmi1 mouse sirna oligo duplex  (OriGene)
N/A
Bmi1 Mouse 3 unique 27mer siRNA duplexes 2 nmol each
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bmi1 rat sirna oligo duplex  (OriGene)
N/A
Bmi1 Rat 3 unique 27mer siRNA duplexes 2 nmol each
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Image Search Results


A Representative images of BMI1 staining (green bodies). Nuclei are counterstained with DAPi (blue staining). BMI1 protein can accumulate in CAP bodies (left panel) or has uniform punctate distribution (PcG bodies, right panel). Scale bar: 5 μm. B Stacked bar plot representing the proportion of CAP and PcG bodies in ALDH br and ALDH neg SUM159 cells sorted according to their cell-cycle phase (G0/G1, S, and G2/M). C , D Representative images (left panels) of BMI1 costaining (green foci) with γH2AX (red foci) for cells harboring CAP bodies ( C ) or PcG bodies ( D ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and γH2AX fluorescent signals. E Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/γH2AX colocalization. F , G Representative images (left panels) of BMI1 costaining (green foci) with RAD51 (red foci) for cells harboring CAP bodies ( F ) or PcG bodies ( G ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and RAD51 fluorescent signals. H Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/RAD51 colocalization. I Representative images of BMI1 staining (green bodies) in ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated (CTRL). Nuclei are counterstained with DAPi (blue staining). J Stacked bar plot representing the proportion of CAP and PcG bodies in replicative ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated. K Bar plots representing the proportion of γH2AX-positive cells for each cell subpopulation (replicative ALDH br and ALDH neg SUM159 cells) following 5-aza treatment or in untreated conditions (CTRL). Statistical test used is Student’s t -test. Data represent mean ± SD.

Journal: Cell Death & Disease

Article Title: BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells

doi: 10.1038/s41419-022-04538-w

Figure Lengend Snippet: A Representative images of BMI1 staining (green bodies). Nuclei are counterstained with DAPi (blue staining). BMI1 protein can accumulate in CAP bodies (left panel) or has uniform punctate distribution (PcG bodies, right panel). Scale bar: 5 μm. B Stacked bar plot representing the proportion of CAP and PcG bodies in ALDH br and ALDH neg SUM159 cells sorted according to their cell-cycle phase (G0/G1, S, and G2/M). C , D Representative images (left panels) of BMI1 costaining (green foci) with γH2AX (red foci) for cells harboring CAP bodies ( C ) or PcG bodies ( D ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and γH2AX fluorescent signals. E Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/γH2AX colocalization. F , G Representative images (left panels) of BMI1 costaining (green foci) with RAD51 (red foci) for cells harboring CAP bodies ( F ) or PcG bodies ( G ). Nuclei are counterstained with DAPi (blue staining). The red lines correspond to the line scans. Pearson’s coefficient evaluated the amount of colocalization. Scale bar: 5 μm. On the right panels, line-scan profiles of the relative intensity of BMI1 and RAD51 fluorescent signals. H Bar plots representing the proportion of replicative ALDH br and ALDH neg SUM159 cells with BMI1/RAD51 colocalization. I Representative images of BMI1 staining (green bodies) in ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated (CTRL). Nuclei are counterstained with DAPi (blue staining). J Stacked bar plot representing the proportion of CAP and PcG bodies in replicative ALDH br and ALDH neg SUM159 cells treated with 5-aza or untreated. K Bar plots representing the proportion of γH2AX-positive cells for each cell subpopulation (replicative ALDH br and ALDH neg SUM159 cells) following 5-aza treatment or in untreated conditions (CTRL). Statistical test used is Student’s t -test. Data represent mean ± SD.

Article Snippet: We used siRNA gene silencing to specially target and knockdown BMI1 gene. siRNA (6442 S, Cell Signaling) was lipoplexed with Lipofectamine RNAiMAX (Life Technologies) in a 96-well culture plate or in a 100 mm tissue-culture dish.

Techniques: Staining